2025 Advantage Cars Prague Open

The 2025 Advantage Cars Prague Open was a professional tennis tournament played on outdoor hard courts. It was the 32nd (men) and 20th (women) editions of the tournament, which were part of the 2025 ATP Challenger Tour and the 2025 ITF Women's World Tennis Tour. It took place in Prague, Czech Republic, between 5 and 11 May 2025.

• Filip Misolic def. Guy den Ouden 6–4, 6–0.

• Francesca Jones def. Ena Shibahara 6–3, 6–4.

• Denys Molchanov / Matěj Vocel def. David Pichler / Jurij Rodionov 7–6^(7–3), 6–3.

• Jasmijn Gimbrère / Denisa Hindová def. Aneta Kučmová / Sapfo Sakellaridi 7–6^(7–5), 7–5.

• ¹ Rankings are as of 21 April 2025.^[1]

The following players received wildcards into the singles main draw:

• Petr Brunclík
• Maxim Mrva
• Mees Röttgering

The following player received entry into the singles main draw as a special exempt:

• Zsombor Piros

The following player received entry into the singles main draw through the College Accelerator Programme:

• Antoine Cornut-Chauvinc

The following player received entry into the singles main draw through the Junior Accelerator Programme:

• Nicolai Budkov Kjær

The following player received entry into the singles main draw as an alternate:

• Jurij Rodionov

The following players received entry from the qualifying draw:

• Hynek Bartoň
• Maxime Chazal
• Guy den Ouden
• Jan Kumstát
• Daniel Rincón
• Vitaliy Sachko

The following player received entry as a lucky loser:

• Sascha Gueymard Wayenburg